6FSE
Mus musculus acetylcholinesterase in complex with 1-(4-(4-Ethylpiperazin-1-yl)piperidin-1-yl)-2-((4'-methoxy-[1,1'-biphenyl]-4-yl)oxy)ethanone dihydrochloride (15)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Acetylcholinesterase | polymer | 548 | 60161.9 | 2 | UniProt (P21836) Pfam (PF00135) In PDB | Mus musculus (Mouse) | AChE |
| 2 | A, B | 1-[4-(4-ethylpiperazin-1-yl)piperidin-1-yl]-2-[4-(4-methoxyphenyl)phenoxy]ethanone | non-polymer | 437.6 | 2 | Chemie (E5K) | |||
| 3 | A | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL | non-polymer | 252.3 | 1 | Chemie (1PG) | |||
| 4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | A, B | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 3 | Chemie (PG0) | |||
| 6 | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 543 (UniProt: P21836)
| PDB | External Database | Details |
|---|---|---|
| Ala 544 | - | expression tag |
| Thr 545 | - | expression tag |
| Gly 546 | - | expression tag |
| Ala 547 | - | expression tag |
| Pro 548 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120323.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1594.0 | |
| All* | Total formula weight | 121917.9 |
