6FRP
Crystal structure of ERK2 in complex with an adenosine derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 364 | 42235.5 | 1 | UniProt (P63086) Pfam (PF00069) | Rattus norvegicus (Norway Rat) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
| 2 | B, C, D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 3 | F, G (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | H (A) | 5'-azido-5'-deoxyadenosine | non-polymer | 292.3 | 1 | Chemie (ZAS) | |||
| 5 | I (A) | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence modifications
A: 1 - 358 (UniProt: P63086)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42235.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 796.9 | |
| All* | Total formula weight | 43032.5 |
