6FQO
Crystal structure of CREBBP bromodomain complexd with DT29
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CREB-binding protein | polymer | 119 | 14223.3 | 2 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
| 2 | A, B | ~{N}-[3-(2,5-dimethyl-3-oxidanylidene-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide | non-polymer | 460.5 | 2 | Chemie (E2T) | |||
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28446.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1045.1 | |
| All* | Total formula weight | 29491.8 |
