6FP1
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kynurenine 3-monooxygenase | polymer | 460 | 50608.3 | 2 | UniProt (Q84HF5) Pfam (PF01494) | Pseudomonas fluorescens | PfKMO,Kynurenine 3-hydroxylase |
| 2 | C, G (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E, I, J, K, L (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 5 | F, M (A, B) | 2-(6-chloranyl-5,7-dimethyl-3-oxidanylidene-1,4-benzoxazin-4-yl)ethanoic acid | non-polymer | 269.7 | 2 | Chemie (E0Q) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 414 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 459 (UniProt: Q84HF5)
| PDB | External Database | Details |
|---|---|---|
| Ser 251 | Cys 252 | engineered mutation |
| Ser 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101216.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2712.0 | |
| All* | Total formula weight | 103928.6 |
