6FOF
Crystal structure of a crystallized variant of h-Gal3: Gal-3[NTS/VII-IX]
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (C, D, E, G, A...) | Galectin-3,Galectin-3 | polymer | 196 | 21209.8 | 12 | UniProt (P17931) Pfam (PF00337) | Homo sapiens (Human) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen,Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
2 | M, N, O, P, Q... (M, N, O, P, Q...) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 12 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
3 | AA, BA, CA, DA, EA... (C, D, E, G, B...) | SULFATE ION | non-polymer | 96.1 | 24 | Chemie (SO4) | |||
4 | AB, BB, CB, DB, EB... (A, B, F, H, I...) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
C, D, E, G, A, B, F, H, I, J, K, L: 55 - 75 (UniProt: P17931)
C, D, E, G, A, B, F, H, I, J, K, L: 76 - 250 (UniProt: P17931)
C, D, E, G, A, B, F, H, I, J, K, L: 76 - 250 (UniProt: P17931)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 254518.2 | |
Branched | Number of molecules | 12 |
Total formula weight | 4107.6 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 2305.5 | |
All* | Total formula weight | 260931.3 |