6FMZ
Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1,4-Bis(2-hydroxyethyl)piperazine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thioredoxin glutathione reductase | polymer | 598 | 65061.1 | 1 | UniProt (G4V8J4) Pfam (PF00462) Pfam (PF07992) Pfam (PF02852) UniProt (by SIFTS) (A0A3Q0KFL1) | Schistosoma mansoni (Blood fluke) | |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanol | non-polymer | 174.2 | 1 | Chemie (DVQ) PubChem (67151) | |||
| 4 | D (A) | water | water | 18.0 | 583 | Chemie (HOH) |
Sequence modifications
A: 1 - 598 (UniProt: G4V8J4)
| PDB | External Database | Details |
|---|---|---|
| Cys 597 | Sec 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65061.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 959.8 | |
| All* | Total formula weight | 66020.9 |
