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6FMN

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((2R,3S,4R,5R)-3,4-dihydroxy-5-methoxytetrahydrofuran-2-yl)methyl)amino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Queuine tRNA-ribosyltransferasepolymer38642925.71UniProt (P28720)
Pfam (PF01702)
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)Guanine insertion enzyme,tRNA-guanine transglycosylase
2B, C, D
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
3E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4F
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5G
(A)
6-azanyl-2-[[(2~{R},3~{S},4~{R},5~{R})-5-methoxy-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-3,7-dihydroimidazo[4,5-g]quinazolin-8-onenon-polymer362.31Chemie (E4E)
6H
(A)
waterwater18.0415Chemie (HOH)
Sequence modifications
A: 1 - 386 (UniProt: P28720)
PDBExternal DatabaseDetails
Lys 312Thr 312engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42925.7
Non-Polymers*Number of molecules6
Total formula weight739.5
All*Total formula weight43665.2
*Water molecules are not included.

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PDB entries from 2025-07-23

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