6FKU
Structure and function of aldehyde dehydrogenase from Thermus thermophilus: An enzyme with an evolutionarily-distinct C-terminal arm (Recombinant protein with shortened C-terminal, in complex with NADP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aldehyde dehydrogenase | polymer | 521 | 57917.6 | 2 | UniProt (Q72KD3) Pfam (PF00171) Pfam (PF05893) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 2 | C, E, F, G, I... (A, B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 6 | Chemie (PGE) | |||
| 3 | D, N, S (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 4 | H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | J, R (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 6 | K, O, Q (A, B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 3 | Chemie (1PE) | |||
| 7 | L, M, T (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 8 | U, V (A, B) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 515 (UniProt: Q72KD3)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115835.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3903.5 | |
| All* | Total formula weight | 119738.6 |
