6FJT
4-chloro-benzamidine in complex with thrombin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Prothrombin | polymer | 28 | 3317.7 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (Human) | Coagulation factor II |
| 2 | B (H) | Prothrombin | polymer | 251 | 28893.3 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (Human) | Coagulation factor II |
| 3 | C (I) | Hirudin variant-2 | polymer | 11 | 1491.5 | 1 | Hirudo medicinalis | ||
| 4 | D, E (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | F (H) | 4-chloranylbenzenecarboximidamide | non-polymer | 154.6 | 1 | Chemie (DKQ) | |||
| 6 | G, H, I (H) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 7 | J (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 8 | K (H) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | L (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 10 | M, N, O (L, H, I) | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
H: 16 - 246 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| - | Trp 511 | deletion |
| - | Thr 512 | deletion |
| - | Ala 513 | deletion |
| - | Asn 514 | deletion |
| - | Val 515 | deletion |
| - | Gly 516 | deletion |
| - | Lys 517 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33702.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 843.2 | |
| All* | Total formula weight | 34545.8 |
