6FI5
Crystal structure of C-terminal modified Tau peptide-hybrid 3.2d with 14-3-3sigma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | THR-PRO-SEP-LEU-PRO-DAL | polymer | 6 | 664.6 | 1 | UniProt (by SIFTS) (P10636) | Homo sapiens | |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F, G, H (A) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | I (B) | (2~{S})-2-(diphenylmethyl)pyrrolidine | non-polymer | 237.3 | 1 | Chemie (60H) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27207.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 389.1 | |
| All* | Total formula weight | 27596.6 |
