6FGV
Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 106 | 12509.0 | 1 | UniProt (Q9UIF9) Pfam (PF00439) | Homo sapiens (Human) | Transcription termination factor I-interacting protein 5,Tip5,hWALp3 |
| 2 | B (A) | ~{N}-[(1-azanylcyclohexyl)methyl]-1-methyl-6-oxidanylidene-pyridine-3-carboxamide | non-polymer | 263.3 | 1 | Chemie (D9T) | |||
| 3 | C (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 1796 - 1899 (UniProt: Q9UIF9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1794 | - | expression tag |
| Met 1795 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12509.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 263.3 | |
| All* | Total formula weight | 12772.4 |
