6FGQ

Ligand complex of RORg LBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Nuclear receptor ROR-gamma	polymer	265	30918.5	2	UniProt (P51449) Pfam (PF00104) In PDB	Homo sapiens (Human)	Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma
2	A, B	methyl 4-[[3-[5-[2-(4-ethylsulfonylphenyl)ethanoylamino]thiophen-3-yl]pyridin-2-yl]oxymethyl]benzoate	non-polymer		550.6	2	Chemie (D9N)
3		water	water		18.0	141	Chemie (HOH)

Sequence modifications

A, B: 265 - 507 (UniProt: P51449)

PDB	External Database	Details
Met 243	-	initiating methionine
His 244	-	expression tag
Asn 245	-	expression tag
His 246	-	expression tag
Asn 247	-	expression tag
His 248	-	expression tag
Asn 249	-	expression tag
His 250	-	expression tag
Asn 251	-	expression tag
His 252	-	expression tag
Asn 253	-	expression tag
His 254	-	expression tag
Asn 255	-	expression tag
Gly 256	-	expression tag
Gly 257	-	expression tag
Glu 258	-	expression tag
Asn 259	-	expression tag
Leu 260	-	expression tag
Tyr 261	-	expression tag
Phe 262	-	expression tag
Gln 263	-	expression tag
Gly 264	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61837.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1101.3
All*	Total formula weight	62938.3

*Water molecules are not included.