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6FGC

Crystal structure of Gephyrin E domain in complex with Artesunate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Gephyrinpolymer41945652.41UniProt (Q03555)
Pfam (PF03453)
Pfam (PF00994)
Pfam (PF03454)
Rattus norvegicus (Rat)Putative glycine receptor-tubulin linker protein
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
4D
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5E
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
6F
(A)
(4R)-2-METHYLPENTANE-2,4-DIOLnon-polymer118.21Chemie (MRD)
7G, H, I, J, K...
(A)
ACETATE IONnon-polymer59.010Chemie (ACT)
8Q
(A)
Artesunatenon-polymer384.41Chemie (D95)
9R
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
10S
(A)
waterwater18.0392Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight45652.4
Non-Polymers*Number of molecules17
Total formula weight1808.9
All*Total formula weight47461.3
*Water molecules are not included.

230083

PDB entries from 2025-01-15

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