6FEQ
Structure of inhibitor-bound ABCG2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | ATP-binding cassette sub-family G member 2 | polymer | 655 | 72385.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) In PDB | Homo sapiens (Human) | Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
| 2 | C, E | 5D3(Fab) light chain variable domain | polymer | 214 | 23594.0 | 2 | Mus musculus (House Mouse) | ||
| 3 | D, F | 5D3(Fab) heavy chain variable domain | polymer | 221 | 23843.6 | 2 | Mus musculus (House Mouse) | ||
| 4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | A | ~{N}-[5-[1-[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1~{H}-isoquinolin-2-yl]ethyl]phenyl]-1,2,3-triazol-4-yl]-2-propanoyl-phenyl]quinoline-2-carboxamide | non-polymer | 798.9 | 1 | Chemie (D6T) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 239647.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1241.3 | |
| All* | Total formula weight | 240888.3 |
