6FD4
Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 14 hours post crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Adenine phosphoribosyltransferase | polymer | 178 | 19411.5 | 2 | UniProt (P07741) Pfam (PF00156) | Homo sapiens (Human) | APRT |
| 2 | C, E (B, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D, F (B, A) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 2 | Chemie (PRP) PubChem (1041) PubChem (7339) PubChem (23616411) PubChem (24771812) PubChem (90395114) PubChem (92962115) PubChem (126970134) | |||
| 4 | G, H (B, A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
B, A: 3 - 180 (UniProt: P07741)
| PDB | External Database | Details |
|---|---|---|
| Phe 105 | Tyr 105 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38822.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 828.8 | |
| All* | Total formula weight | 39651.7 |
