6FBQ
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human MEp DR1 Response Element, pH 7.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinoic acid receptor RXR-alpha | polymer | 87 | 10262.9 | 2 | UniProt (P19793) Pfam (PF00105) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | C (C) | DNA (5'-D(*CP*TP*GP*GP*GP*TP*CP*AP*AP*AP*GP*TP*TP*CP*AP*TP*C)-3') | polymer | 17 | 5202.4 | 1 | Homo sapiens | ||
| 3 | D (D) | DNA (5'-D(*GP*AP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*CP*CP*CP*AP*G)-3') | polymer | 17 | 5211.4 | 1 | Homo sapiens | ||
| 4 | E, F, H, I (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | G (A) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 1 | Chemie (MPO) | |||
| 6 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 430 | Chemie (HOH) |
Sequence modifications
A, B: 130 - 212 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
| Ser 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30939.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 470.9 | |
| All* | Total formula weight | 31410.5 |
