6FBP
Human Methionine Adenosyltransferase II mutant (S114A) in P22121 crystal form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | S-adenosylmethionine synthase isoform type-2 | polymer | 395 | 43704.6 | 2 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | Homo sapiens (Human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
| 2 | C, L (A, B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 3 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | E, H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | F, N (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 6 | G, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | J (B) | (DIPHOSPHONO)AMINOPHOSPHONIC ACID | non-polymer | 257.0 | 1 | Chemie (PPK) | |||
| 8 | M (B) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 9 | O, P (A, B) | water | water | 18.0 | 488 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 395 (UniProt: P31153)
| PDB | External Database | Details |
|---|---|---|
| Ala 114 | Ser 114 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87409.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1284.7 | |
| All* | Total formula weight | 88694.0 |






