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6FBP

Human Methionine Adenosyltransferase II mutant (S114A) in P22121 crystal form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
S-adenosylmethionine synthase isoform type-2polymer39543704.62UniProt (P31153)
Pfam (PF00438)
Pfam (PF02772)
Pfam (PF02773)
Homo sapiens (Human)AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II
2C, L
(A, B)
TETRAETHYLENE GLYCOLnon-polymer194.22Chemie (PG4)
3D
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4E, H, I
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5F, N
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
6G, K
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7J
(B)
(DIPHOSPHONO)AMINOPHOSPHONIC ACIDnon-polymer257.01Chemie (PPK)
8M
(B)
ADENOSINEnon-polymer267.21Chemie (ADN)
9O, P
(A, B)
waterwater18.0488Chemie (HOH)
Sequence modifications
A, B: 1 - 395 (UniProt: P31153)
PDBExternal DatabaseDetails
Ala 114Ser 114conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight87409.3
Non-Polymers*Number of molecules12
Total formula weight1284.7
All*Total formula weight88694.0
*Water molecules are not included.

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PDB entries from 2025-08-06

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