6F7L
Crystal structure of LkcE R326Q mutant in complex with its substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Amine oxidase LkcE | polymer | 442 | 49318.3 | 2 | UniProt (Q83X90) Pfam (PF01593) | Streptomyces rochei (Streptomyces parvullus) | |
| 2 | C, I (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, E, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | F, N (A, B) | [(2~{S},5~{R},8~{S},11~{S})-1-[(2~{R},3~{R},5~{R},6~{S})-3,5-dimethyl-6-oxidanyl-4-oxidanylidene-oxan-2-yl]-5,11-dimeth yl-8-oxidanyl-13-[[(2~{S})-2-oxidanylpropanoyl]amino]tridecan-2-yl] ethanoate | non-polymer | 515.7 | 2 | Chemie (CWH) | |||
| 5 | G, H, O, P, Q... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 6 | K, L, M (B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 438 (UniProt: Q83X90)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gln 54 | Arg 54 | conflict |
| Gln 326 | Arg 326 | engineered mutation |
| Pro 424 | Leu 424 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 98636.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3544.5 | |
| All* | Total formula weight | 102181.0 |
