6F4S
Human JMJD5 (N308C) in complex with Mn(II), 2OG and RCCD1 (139-143) (complex-4)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | JmjC domain-containing protein 5 | polymer | 255 | 29527.3 | 1 | UniProt (Q8N371) Pfam (PF13621) In PDB | Homo sapiens (Human) | LYSINE-SPECIFIC DEMETHYLASE 8, JUMONJI DOMAIN-CONTAINING PROTEIN 5 |
2 | B | RCC1 domain-containing protein 1 | polymer | 5 | 583.7 | 1 | UniProt (A6NED2) In PDB | Homo sapiens | |
3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
4 | A | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
5 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
A: 183 - 416 (UniProt: Q8N371)
PDB | External Database | Details |
---|---|---|
His 162 | - | expression tag |
His 163 | - | expression tag |
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
His 167 | - | expression tag |
Ser 168 | - | expression tag |
Ser 169 | - | expression tag |
Gly 170 | - | expression tag |
Val 171 | - | expression tag |
Asp 172 | - | expression tag |
Leu 173 | - | expression tag |
Gly 174 | - | expression tag |
Thr 175 | - | expression tag |
Glu 176 | - | expression tag |
Asn 177 | - | expression tag |
Leu 178 | - | expression tag |
Tyr 179 | - | expression tag |
Phe 180 | - | expression tag |
Gln 181 | - | expression tag |
Ser 182 | - | expression tag |
Ala 217 | Cys 217 | engineered mutation |
Ala 232 | Cys 232 | engineered mutation |
Cys 308 | Asn 308 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30110.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 415.3 | |
All* | Total formula weight | 30526.2 |