6F4L
Structure of quinolinate synthase with inhibitor-derived quinolinate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Quinolinate synthase A | polymer | 305 | 34656.6 | 1 | UniProt (Q9X1X7) Pfam (PF02445) In PDB | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | |
| 2 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 3 | A | QUINOLINIC ACID | non-polymer | 167.1 | 1 | Chemie (NTM) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | A | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 1 | Chemie (NHE) | |||
| 6 | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: Q9X1X7)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Arg 219 | Lys 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34656.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 761.5 | |
| All* | Total formula weight | 35418.1 |
