6F3T

Crystal structure of the human TAF5-TAF6-TAF9 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Transcription initiation factor TFIID subunit 5	polymer	608	68950.4	4	UniProt (Q15542) Pfam (PF04494) Pfam (PF00400) In PDB	Homo sapiens (Human)	Transcription initiation factor TFIID 100 kDa subunit,TAFII100
2	E, G, I, K	Transcription initiation factor TFIID subunit 6	polymer	94	10888.7	4	UniProt (P49848) Pfam (PF02969) In PDB	Homo sapiens (Human)	RNA polymerase II TBP-associated factor subunit E,Transcription initiation factor TFIID 70 kDa subunit,TAFII70,Transcription initiation factor TFIID 80 kDa subunit,TAFII80
3	F, H, J, L	Transcription initiation factor TFIID subunit 9	polymer	116	13325.2	4	UniProt (Q16594) Pfam (PF02291) In PDB	Homo sapiens (Human)	RNA polymerase II TBP-associated factor subunit G,STAF31/32,Transcription initiation factor TFIID 31 kDa subunit,TAFII31,Transcription initiation factor TFIID 32 kDa subunit,TAFII32
4	A, B, C, D	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL)
5		water	water		18.0	391	Chemie (HOH)

Sequence modifications

A, B, C, D: 194 - 800 (UniProt: Q15542)

PDB	External Database	Details
Gly 193	-	expression tag
Ser 400	Pro 400	conflict

E, G, I, K: 5 - 92 (UniProt: P49848)

PDB	External Database	Details
Arg 93	-	expression tag
Leu 94	-	expression tag
Arg 95	-	expression tag
Arg 96	-	expression tag
Arg 97	-	expression tag
Ala 98	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	372657.4
Non-Polymers*	Number of molecules	7
	Total formula weight	248.2
All*	Total formula weight	372905.6

*Water molecules are not included.