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6F3E

IRAK4 IN COMPLEX WITH inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BInterleukin-1 receptor-associated kinase 4polymer29533315.72UniProt (Q9NWZ3)
Pfam (PF07714)
In PDB
Homo sapiens (Human)IRAK-4,Renal carcinoma antigen NY-REN-64
2ASULFATE IONnon-polymer96.11Chemie (SO4)
3A, B2-[(3~{R})-12-(4-morpholin-4-ylcyclohexyl)oxy-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9,11-tetraen-3-yl]ethanamidenon-polymer416.52Chemie (CJQ)
4waterwater18.09Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66631.3
Non-Polymers*Number of molecules3
Total formula weight929.1
All*Total formula weight67560.5
*Water molecules are not included.

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PDB entries from 2024-08-14

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