6F3B
Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-[(4-methylphenyl)methyl]urea inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carbonic anhydrase 1 | polymer | 261 | 28906.2 | 2 | UniProt (P00915) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase I,Carbonic anhydrase B,CAB,Carbonic anhydrase I,CA-I |
| 2 | C, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, I (A, B) | 1-[(4-methylphenyl)methyl]-3-(2-oxidanyl-5-sulfamoyl-phenyl)urea | non-polymer | 335.4 | 2 | Chemie (CJK) | |||
| 4 | E, F (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | G, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57812.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1195.9 | |
| All* | Total formula weight | 59008.3 |
