6F2T
Crystal structure of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | polymer | 749 | 85399.4 | 2 | UniProt (P97675) Pfam (PF01663) | Rattus norvegicus (Rat) | E-NPP 3,B10,Phosphodiesterase I beta,PD-Ibeta,Phosphodiesterase I/nucleotide pyrophosphatase 3,RB13-6 antigen |
2 | C, D, E (C, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
3 | F, G (F, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
4 | H, N (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
5 | I, J, O, P (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
6 | K, Q (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
7 | L, M, R, S (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
8 | T, U (A, B) | water | water | 18.0 | 474 | Chemie (HOH) |
Sequence modifications
A, B: 140 - 875 (UniProt: P97675)
PDB | External Database | Details |
---|---|---|
Ala 136 | - | expression tag |
Glu 137 | - | expression tag |
Thr 138 | - | expression tag |
Gly 139 | - | expression tag |
Val 201 | Met 201 | variant |
Asn 596 | Ser 596 | variant |
Arg 597 | Gly 597 | variant |
Gly 876 | - | expression tag |
Thr 877 | - | expression tag |
Lys 878 | - | expression tag |
His 879 | - | expression tag |
His 880 | - | expression tag |
His 881 | - | expression tag |
His 882 | - | expression tag |
His 883 | - | expression tag |
His 884 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 170798.8 | |
Branched | Number of molecules | 5 |
Total formula weight | 2446.3 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1416.6 | |
All* | Total formula weight | 174661.6 |