6EX7
Crystal structure of NDM-1 metallo-beta-lactamase in complex with Cd ions and a hydrolyzed beta-lactam ligand - new refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metallo-beta-lactamase type 2 | polymer | 243 | 25717.9 | 2 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | B2 metallo-beta-lactamase,Beta-lactamase type II,Metallo-beta-lactamase NDM-1,Metallo-beta-lactamase type II,New Delhi metallo-beta-lactamase-1,NDM-1 |
| 2 | C, D, E, I, J... (A, B) | CADMIUM ION | non-polymer | 112.4 | 6 | Chemie (CD) | |||
| 3 | F, L, M (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | G, N (A, B) | UNKNOWN LIGAND | non-polymer | 189.2 | 2 | Chemie (UNL) | |||
| 5 | H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | O (B) | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL | non-polymer | 164.2 | 1 | Chemie (TOE) | |||
| 7 | P (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51435.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1579.7 | |
| All* | Total formula weight | 53015.5 |
