6ES7

Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Nuclear receptor coactivator 3	polymer	44	4708.1	1	UniProt (Q9Y6Q9) Pfam (PF08815)	Homo sapiens (Human)	NCoA-3,ACTR,Amplified in breast cancer 1 protein,AIB-1,CBP-interacting protein,pCIP,Class E basic helix-loop-helix protein 42,bHLHe42,Receptor-associated coactivator 3,RAC-3,Steroid receptor coactivator protein 3,SRC-3,Thyroid hormone receptor activator molecule 1,TRAM-1
2	B (B)	CREB-binding protein	polymer	50	5530.4	1	UniProt (Q92793) Pfam (PF09030)	Homo sapiens (Human)

Sequence modifications

A: 1040 - 1081 (UniProt: Q9Y6Q9)

PDB	External Database	Details
Gly 1038	-	expression tag
Ser 1039	-	expression tag

B: 2061 - 2109 (UniProt: Q92793)

PDB	External Database	Details
Gly 2060	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	10238.5
All*	Total formula weight	10238.5

*Water molecules are not included.