6ERW
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013 and Fasudil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41193.7 | 1 | UniProt (P25321) Pfam (PF00069) | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
| 2 | B (D) | UPF0418 protein FAM164A | polymer | 18 | 1973.2 | 1 | UniProt (G3HK48) | Cricetulus griseus | |
| 3 | C (A) | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE | non-polymer | 291.4 | 1 | Chemie (M77) | |||
| 4 | D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | E, F (A, D) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43166.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 409.5 | |
| All* | Total formula weight | 43576.5 |
