6EPE
Substrate processing state 26S proteasome (SPS2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proteasome subunit alpha type-6 | polymer | 246 | 27432.5 | 1 | UniProt (P60901) Pfam (PF00227) Pfam (PF10584) | Rattus norvegicus (Rat) | Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain |
| 2 | B (B) | Proteasome subunit alpha type-2 | polymer | 234 | 25955.5 | 1 | UniProt (P17220) Pfam (PF10584) Pfam (PF00227) | Rattus norvegicus (Norway Rat) | Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3 |
| 3 | C (C) | Proteasome subunit alpha type-4 | polymer | 261 | 29539.8 | 1 | UniProt (P21670) Pfam (PF10584) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L |
| 4 | D (D) | Proteasome subunit alpha type-7 | polymer | 254 | 28369.4 | 1 | UniProt (P48004) Pfam (PF10584) Pfam (PF00227) | Rattus norvegicus (Rat) | Proteasome subunit RC6-1 |
| 5 | E (E) | Proteasome subunit alpha type-5 | polymer | 241 | 26416.8 | 1 | UniProt (P34064) Pfam (PF10584) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain |
| 6 | F (F) | Proteasome subunit alpha type-1 | polymer | 263 | 29557.5 | 1 | UniProt (P18420) Pfam (PF10584) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain |
| 7 | G (G) | Proteasome subunit alpha type-3 | polymer | 255 | 28456.3 | 1 | UniProt (P18422) Pfam (PF10584) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8,Proteasome subunit K |
| 8 | H (1) | Proteasome subunit beta type-6 | polymer | 238 | 25309.6 | 1 | UniProt (P28073) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain delta chain,Multicatalytic endopeptidase complex delta chain,Proteasome chain 5,Proteasome delta chain,Proteasome subunit Y |
| 9 | I (2) | Proteasome subunit beta type-7 | polymer | 277 | 29963.5 | 1 | UniProt (Q9JHW0) Pfam (PF00227) Pfam (PF12465) | Rattus norvegicus (Rat) | Macropain chain Z,Multicatalytic endopeptidase complex chain Z,Proteasome subunit Z |
| 10 | J (3) | Proteasome subunit beta type-3 | polymer | 205 | 22988.9 | 1 | UniProt (P40112) Pfam (PF00227) | Rattus norvegicus (Rat) | Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain |
| 11 | K (4) | Proteasome subunit beta type-2 | polymer | 201 | 22941.4 | 1 | UniProt (P40307) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7-I,Proteasome component C7-I |
| 12 | L (5) | Proteasome subunit beta type-5 | polymer | 263 | 28615.4 | 1 | UniProt (P28075) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain epsilon chain,Multicatalytic endopeptidase complex epsilon chain,Proteasome chain 6,Proteasome epsilon chain,Proteasome subunit X |
| 13 | M (6) | Proteasome subunit beta type-1 | polymer | 240 | 26511.3 | 1 | UniProt (P18421) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain subunit C5,Multicatalytic endopeptidase complex subunit C5,Proteasome component C5,Proteasome gamma chain |
| 14 | N (7) | Proteasome subunit beta type-4 | polymer | 263 | 29226.2 | 1 | UniProt (P34067) Pfam (PF00227) | Rattus norvegicus (Rat) | Macropain beta chain,Multicatalytic endopeptidase complex beta chain,Proteasome beta chain,Proteasome chain 3,RN3 |
| 15 | O (W) | 26S proteasome subunit S5a | polymer | 377 | 40775.6 | 1 | UniProt (Q9ESH1) Pfam (PF13519) Pfam (PF02809) | Rattus norvegicus (Rat) | Psmd4 protein |
| 16 | P (V) | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 | polymer | 310 | 34620.0 | 1 | UniProt (Q4V8E2) Pfam (PF01398) | Rattus norvegicus (Rat) | Proteasome 26S subunit,non-ATPase 14,Psmd14 protein,RCG26455,isoform CRA_b |
| 17 | Q (T) | Proteasome 26S subunit, non-ATPase 8 | polymer | 353 | 39932.1 | 1 | UniProt (F1LMQ3) Pfam (PF10075) | Rattus norvegicus (Rat) | |
| 18 | R (Y) | RCG28037 | polymer | 70 | 8284.6 | 1 | UniProt (D3ZHW9) Pfam (PF05160) | Rattus norvegicus (Rat) | SEM1,26S proteasome complex subunit |
| 19 | S (Z) | 26S proteasome non-ATPase regulatory subunit 2 | polymer | 908 | 100300.5 | 1 | UniProt (Q4FZT9) Pfam (PF17781) Pfam (PF01851) Pfam (PF18051) | Rattus norvegicus (Rat) | |
| 20 | T (N) | 26S proteasome non-ATPase regulatory subunit 1 | polymer | 953 | 105870.1 | 1 | UniProt (O88761) Pfam (PF21505) Pfam (PF01851) Pfam (PF13646) Pfam (PF18004) | Rattus norvegicus (Rat) | 26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112 |
| 21 | U (S) | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3 | polymer | 530 | 60778.2 | 1 | UniProt (Q5U2S7) Pfam (PF01399) Pfam (PF08375) UniProt (by SIFTS) (A6HIT6) | Rattus norvegicus (Rat) | Proteasome (Prosome,macropain) 26S subunit,non-ATPase,3,isoform CRA_b,Proteasome 26S subunit,non-ATPase 3 |
| 22 | V (P) | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 | polymer | 456 | 53011.2 | 1 | UniProt (Q5XIC6) Pfam (PF22241) Pfam (PF01399) Pfam (PF18098) | Rattus norvegicus (Rat) | Proteasome 26S subunit,non-ATPase 12 |
| 23 | W (Q) | 26S proteasome non-ATPase regulatory subunit 11 | polymer | 422 | 47526.7 | 1 | UniProt (F1LMZ8) Pfam (PF18055) Pfam (PF01399) Pfam (PF18503) | Rattus norvegicus (Rat) | 26S proteasome regulatory subunit RPN6 |
| 24 | X (R) | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6 | polymer | 389 | 45658.4 | 1 | UniProt (Q6PCT9) Pfam (PF10602) Pfam (PF01399) Pfam (PF21154) | Rattus norvegicus (Rat) | Proteasome (Prosome,macropain) 26S subunit,non-ATPase,6,isoform CRA_a,Proteasome 26S subunit,non-ATPase 6 |
| 25 | Y (U) | Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Predicted) | polymer | 320 | 36551.8 | 1 | UniProt (D4AEH3) Pfam (PF01398) Pfam (PF13012) | Rattus norvegicus (Rat) | Proteasome 26S subunit,non-ATPase 7 |
| 26 | Z (O) | 26S proteasome non-ATPase regulatory subunit 13 | polymer | 376 | 42867.2 | 1 | UniProt (B0BN93) Pfam (PF22037) Pfam (PF01399) | Rattus norvegicus (Rat) | 26S proteasome regulatory subunit RPN9,26S proteasome regulatory subunit S11,26S proteasome regulatory subunit p40.5 |
| 27 | AA (H) | 26S proteasome regulatory subunit 7 | polymer | 433 | 48640.7 | 1 | UniProt (Q63347) Pfam (PF21236) Pfam (PF00004) Pfam (PF17862) | Rattus norvegicus (Rat) | 26S proteasome AAA-ATPase subunit RPT1,Proteasome 26S subunit ATPase 2,Protein MSS1 |
| 28 | BA (I) | 26S proteasome regulatory subunit 4 | polymer | 440 | 49260.5 | 1 | UniProt (P62193) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) | Rattus norvegicus (Rat) | P26s4,26S proteasome AAA-ATPase subunit RPT2,Proteasome 26S subunit ATPase 1 |
| 29 | CA (K) | 26S proteasome regulatory subunit 6B | polymer | 418 | 47468.2 | 1 | UniProt (Q63570) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) | Rattus norvegicus (Rat) | 26S proteasome AAA-ATPase subunit RPT3,Proteasome 26S subunit ATPase 4,S6 ATPase,Tat-binding protein 7,TBP-7 |
| 30 | DA (L) | Proteasome 26S subunit, ATPase 6 | polymer | 403 | 45867.0 | 1 | UniProt (G3V6W6) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) | Rattus norvegicus (Rat) | RCG61291 |
| 31 | EA (M) | 26S proteasome regulatory subunit 6A | polymer | 442 | 49611.8 | 1 | UniProt (Q6P6U2) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) UniProt (by SIFTS) (Q63569) | Rattus norvegicus (Rat) | Proteasome (Prosome,macropain) 26S subunit,ATPase 3,isoform CRA_a |
| 32 | FA (J) | 26S proteasome regulatory subunit 8 | polymer | 406 | 45694.0 | 1 | UniProt (P62198) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) | Rattus norvegicus (Rat) | 26S proteasome AAA-ATPase subunit RPT6,Proteasome 26S subunit ATPase 5,Proteasome subunit p45,Thyroid hormone receptor-interacting protein 1,TRIP1,p45/SUG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 32 |
| Total formula weight | 1284003.1 | |
| All* | Total formula weight | 1284003.1 |
