6EO9
Crystal structure of thrombin in complex with a novel glucose-conjugated potent inhibitor
Replaces: 4NZEEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Prothrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (Human) | Coagulation factor II |
| 2 | B (L) | Prothrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (Human) | Coagulation factor II |
| 3 | C (I) | Hirudin variant-2 | polymer | 12 | 1534.6 | 1 | UniProt (P09945) | Hirudo medicinalis (Medicinal leech) | |
| 4 | D, E, F, G, H... (H) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 6 | Chemie (DMS) | |||
| 5 | J (H) | N-(2-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methoxy}-6-{3-[(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)oxy]propoxy}phenyl)-1-(propan-2-yl)piperidine-4-carboxamide | non-polymer | 864.4 | 1 | Chemie (2OJ) | |||
| 6 | K, L (H, L) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35411.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1333.2 | |
| All* | Total formula weight | 36744.5 |
