6ELG

Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetonitrile

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Trp operon repressor	polymer	116	13557.5	2	UniProt (P0A881) Pfam (PF01371) In PDB	Escherichia coli
2	A, B	1H-indol-3-ylacetonitrile	non-polymer		156.2	2	Chemie (3BO)
3		water	water		18.0	378	Chemie (HOH)

Sequence modifications

A, B: 1 - 108 (UniProt: P0A881)

PDB	External Database	Details
Phe 42	Met 42	engineered mutation
Leu 44	Thr 44	engineered mutation
Ile 81	Thr 81	engineered mutation
Tyr 88	Ser 88	engineered mutation
Leu 109	-	expression tag
Glu 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27114.9
Non-Polymers*	Number of molecules	2
	Total formula weight	312.4
All*	Total formula weight	27427.3

*Water molecules are not included.