6ELB

Tryptophan Repressor TrpR from E.coli variant M42F T44L T81M N87G S88Y with Indole-3-acetic acid as ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Trp operon repressor	polymer	116	13518.5	2	UniProt (P0A881) Pfam (PF01371) In PDB	Escherichia coli
2	A, B	1H-INDOL-3-YLACETIC ACID	non-polymer		175.2	2	Chemie (IAC)
3		water	water		18.0	294	Chemie (HOH)

Sequence modifications

A, B: 1 - 108 (UniProt: P0A881)

PDB	External Database	Details
Phe 42	Met 42	engineered mutation
Leu 44	Thr 44	engineered mutation
Met 81	Thr 81	engineered mutation
Gly 87	Asn 87	engineered mutation
Tyr 88	Ser 88	engineered mutation
Leu 109	-	expression tag
Glu 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27036.9
Non-Polymers*	Number of molecules	2
	Total formula weight	350.4
All*	Total formula weight	27387.3

*Water molecules are not included.