6EKM

Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitotic spindle assembly checkpoint protein MAD2B	polymer	211	24473.5	1	UniProt (Q9D752) Pfam (PF02301) In PDB	Mus musculus (Mouse)	Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2
2	B	DNA polymerase zeta catalytic subunit	polymer	28	3205.9	1	UniProt (O60673) In PDB	Homo sapiens (Human)	Protein reversionless 3-like,hREV3
3		water	water		18.0	21	Chemie (HOH)

Sequence modifications

A: 1 - 211 (UniProt: Q9D752)

PDB	External Database	Details
Ser 11	Phe 11	engineered mutation
Ala 12	Gly 12	engineered mutation
Lys 132	Val 132	engineered mutation
Val 133	Cys 133	engineered mutation
Lys 135	Ala 135	engineered mutation

B: 1989 - 2014 (UniProt: O60673)

PDB	External Database	Details
Met 1987	-	initiating methionine
Gly 1988	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27679.5
All*	Total formula weight	27679.5

*Water molecules are not included.