6EJ2
BACE1 compound 28
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-secretase 1 | polymer | 501 | 55815.5 | 1 | UniProt (P56817) Pfam (PF00026) | Homo sapiens (Human) | Aspartyl protease 2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2 |
| 2 | B (A) | compound 28 | non-polymer | 378.5 | 1 | Chemie (B7E) | |||
| 3 | C (A) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A: 349 - 849 (UniProt: P56817)
| PDB | External Database | Details |
|---|---|---|
| Asp 786 | Leu 438 | conflict |
| Leu 787 | Asp 439 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55815.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 378.5 | |
| All* | Total formula weight | 56194.0 |
