6EIL
DYRK1A in complex with XMD8-49
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DYRK1A | polymer | 368 | 42654.0 | 4 | UniProt (Q13627) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | E, F, G (A, B, D) | [3-azanyl-6-(5-azanyl-2-methoxy-phenyl)pyrazin-2-yl]-pyridin-3-yl-methanone | non-polymer | 321.3 | 3 | Chemie (B6B) | |||
| 3 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 430 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 126 - 490 (UniProt: Q13627)
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | - | expression tag |
| Ala 124 | - | expression tag |
| Ser 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170616.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 964.0 | |
| All* | Total formula weight | 171580.0 |
