6EIJ
DYRK1A in complex with HG-8-60-1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | polymer | 368 | 42654.0 | 4 | UniProt (Q13627) Pfam (PF00069) In PDB | Homo sapiens (Human) | Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog |
2 | A, B, C, D | ~{N}-[5-[3-(2-morpholin-4-ylethylcarbamoylamino)phenyl]-[1,3]thiazolo[5,4-b]pyridin-2-yl]cyclopropanecarboxamide | non-polymer | 466.6 | 4 | Chemie (B5Z) | |||
3 | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 126 - 490 (UniProt: Q13627)
PDB | External Database | Details |
---|---|---|
Gly 123 | - | expression tag |
Ala 124 | - | expression tag |
Ser 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 170616.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1866.2 | |
All* | Total formula weight | 172482.2 |