6EG1
Crystal structure of Dpr2 Ig1-Ig2 in complex with DIP-Theta Ig1-Ig3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Defective proboscis extension response 2, isoform F | polymer | 231 | 25771.3 | 2 | UniProt (Q59DZ4) Pfam (PF07686) | Drosophila melanogaster (Fruit fly) | Dpr2, Defective proboscis extension response 2,isoform G |
| 2 | B, D (B, D) | Dpr-interacting protein theta | polymer | 302 | 34110.2 | 2 | UniProt (Q9VMN6) Pfam (PF07686) Pfam (PF13927) | Drosophila melanogaster (Fruit fly) | DIP-Theta, FI23919p1 |
| 3 | E, I, J, K, N (E, I, J, K, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 5 | In PDB GlyTouCan (G21290RB) | |||
| 4 | F, L (F, L) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 2 | In PDB GlyTouCan (G42466VF) | |||
| 5 | G, M (G, M) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB GlyTouCan (G32152BH) | |||
| 6 | H (H) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 7 | O (O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 8 | P, Q (C) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 9 | R, V (C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 10 | S, T (C) | (R,R)-2,3-BUTANEDIOL | non-polymer | 90.1 | 2 | Chemie (BU3) | |||
| 11 | U (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 12 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, C: 103 - 323 (UniProt: Q59DZ4)
B, D: 128 - 423 (UniProt: Q9VMN6)
| PDB | External Database | Details |
|---|---|---|
| Gly 101 | - | expression tag |
| Ser 102 | - | expression tag |
| His 324 | - | expression tag |
| His 325 | - | expression tag |
| His 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 424 | - | expression tag |
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
| His 429 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119763.0 | |
| Branched | Number of molecules | 11 |
| Total formula weight | 6899.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 991.9 | |
| All* | Total formula weight | 127654.3 |
