6ECO

Hexamer-2-Foldon HIV-1 capsid platform

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HIV-1 capsid platform protein	polymer	253	28129.2	1	UniProt (P04591) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus type 1 (HIV-1)	Pr55Gag
2	B (D)	HIV-1 capsid platform protein	polymer	221	24788.4	1	UniProt (P04591) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus type 1 (HIV-1)	Pr55Gag

Sequence modifications

A: 1 - 226 (UniProt: P04591)

PDB	External Database	Details
Leu 6	Ile 138	conflict
Cys 45	Glu 177	engineered mutation
Glu 54	Thr 186	engineered mutation
Leu 83	Val 215	conflict
His 120	Asn 252	conflict
Gly 208	Ala 340	conflict
Gly 227	-	expression tag
Tyr 228	-	expression tag
Ile 229	-	expression tag
Pro 230	-	expression tag
Glu 231	-	expression tag
Ala 232	-	expression tag
Pro 233	-	expression tag
Arg 234	-	expression tag
Asp 235	-	expression tag
Gly 236	-	expression tag
Gln 237	-	expression tag
Ala 238	-	expression tag
Tyr 239	-	expression tag
Val 240	-	expression tag
Arg 241	-	expression tag
Lys 242	-	expression tag
Asp 243	-	expression tag
Gly 244	-	expression tag
Glu 245	-	expression tag
Trp 246	-	expression tag
Val 247	-	expression tag
Leu 248	-	expression tag
Leu 249	-	expression tag
Ser 250	-	expression tag
Thr 251	-	expression tag
Phe 252	-	expression tag
Leu 253	-	expression tag

D: 1 - 221 (UniProt: P04591)

PDB	External Database	Details
Leu 6	Ile 138	conflict
Cys 14	Ala 146	engineered mutation
Glu 42	Ala 174	engineered mutation
Leu 83	Val 215	conflict
His 120	Asn 252	conflict
Asp 204	Ala 336	engineered mutation
Gly 208	Ala 340	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52917.6
All*	Total formula weight	52917.6

*Water molecules are not included.