6ECK

Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Pyruvate kinase PKLR	polymer	550	59910.5	2	UniProt (P12928) Pfam (PF00224) Pfam (PF02887) In PDB	Rattus norvegicus (Rat)	L-PK,Pyruvate kinase isozymes L/R
2	A, B	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	2	Chemie (FBP)
3	A, B	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	B	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)
7	B	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
8		water	water		18.0	387	Chemie (HOH)

Sequence modifications

A, B: 1 - 543 (UniProt: P12928)

PDB	External Database	Details
His 0	-	expression tag
His 544	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119820.9
Non-Polymers*	Number of molecules	12
	Total formula weight	1694.2
All*	Total formula weight	121515.2

*Water molecules are not included.