6ECK

Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Pyruvate kinase PKLR	polymer	550	59910.5	2	UniProt (P12928) Pfam (PF00224) Pfam (PF02887)	Rattus norvegicus (Rat)	L-PK,Pyruvate kinase isozymes L/R
2	C, J (A, B)	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	2	Chemie (FBP) PubChem (718) PubChem (10267) PubChem (172313) PubChem (440117) PubChem (5702629) PubChem (12800340) PubChem (16219368) PubChem (24802138) PubChem (46937007) PubChem (445557) PubChem (92209487) PubChem (124383956) PubChem (124540446) PubChem (135053794) PubChem (89534552) PubChem (92209485) PubChem (92209486) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795)
3	D, E, K (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL) PubChem (753)
4	F, M (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG) PubChem (8117)
5	G, H, I (A)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	L (B)	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC) PubChem (31348)
7	N (B)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
8	O, P (A, B)	water	water		18.0	387	Chemie (HOH)

Sequence modifications

A, B: 1 - 543 (UniProt: P12928)

PDB	External Database	Details
His 0	-	expression tag
His 544	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119820.9
Non-Polymers*	Number of molecules	12
	Total formula weight	1694.2
All*	Total formula weight	121515.2

*Water molecules are not included.