6EC2

Structure of HIV-1 CA 1/3-hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, F)	Capsid protein p24	polymer	231	25457.2	2	UniProt (P04591) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus type 1 (HIV-1)	Pr55Gag, HIV-1 CA 1/3-hexamer
2	B, D (C, G)	Capsid protein p24	polymer	231	25545.3	2	UniProt (P04591) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus type 1 (HIV-1)	Pr55Gag, HIV-1 CA 1/3-hexamer
3	E, F, G (A, C, F)	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
4	H, I, J (A, C, F)	water	water		18.0	14	Chemie (HOH)

Sequence modifications

A, F: 1 - 231 (UniProt: P04591)

PDB	External Database	Details
Leu 6	Ile 138	conflict
Cys 45	Glu 177	engineered mutation
Glu 54	Thr 186	engineered mutation
Leu 83	Val 215	conflict
His 120	Asn 252	conflict
Ala 184	Trp 316	engineered mutation
Ala 185	Met 317	engineered mutation
Gly 208	Ala 340	conflict

C, G: 1 - 231 (UniProt: P04591)

PDB	External Database	Details
Leu 6	Ile 138	conflict
Cys 14	Ala 146	engineered mutation
Glu 42	Ala 174	engineered mutation
Leu 83	Val 215	conflict
His 120	Asn 252	conflict
Ala 184	Trp 316	engineered mutation
Ala 185	Met 317	engineered mutation
Gly 208	Ala 340	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	102005.0
Non-Polymers*	Number of molecules	3
	Total formula weight	177.1
All*	Total formula weight	102182.1

*Water molecules are not included.