6EC0
Crystal structure of the wild-type heterocomplex between coil 1B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Keratin 1 | polymer | 107 | 12764.2 | 1 | UniProt (H6VRG1) Pfam (PF00038) | Homo sapiens (Human) | |
| 2 | B (B) | Keratin, type I cytoskeletal 10 | polymer | 104 | 12121.5 | 1 | UniProt (P13645) Pfam (PF00038) | Homo sapiens (Human) | Cytokeratin-10,CK-10,Keratin-10,K10 |
| 3 | C, D, E, G (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 4 | F, H (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 5 | I, J (B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 226 - 331 (UniProt: H6VRG1)
B: 195 - 296 (UniProt: P13645)
| PDB | External Database | Details |
|---|---|---|
| Met 225 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 193 | - | expression tag |
| Ser 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24885.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 684.9 | |
| All* | Total formula weight | 25570.6 |
