6EBM

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, D, F, H)	Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera	polymer	513	58905.8	4	UniProt (P63142) UniProt (Q63099) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885)	Rattus norvegicus (Rat)	RAK,RBK2,RCK5,Voltage-gated potassium channel subunit Kv1.2,CDRK,Voltage-gated potassium channel subunit Kv2.2,RAK,RBK2,RCK5,Voltage-gated potassium channel subunit Kv1.2

Sequence modifications

B, D, F, H: 1 - 266 (UniProt: P63142)

PDB	External Database	Details
Met -17	-	expression tag
Ala -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
His 15	Leu 15	conflict
Gln 207	Asn 207	conflict

B, D, F, H: 267 - 298 (UniProt: Q63099)
B, D, F, H: 299 - 495 (UniProt: P63142)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	235623.3
All*	Total formula weight	235623.3

*Water molecules are not included.