6E99
Crystal structure of Protein Kinase A in complex with the PKI peptide and an amino-pyridinylbenzamide based inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 351 | 40837.6 | 1 | UniProt (P00517) Pfam (PF00069) In PDB | Bos taurus (Bovine) | PKA C-alpha |
| 2 | B | PKI peptide | polymer | 18 | 1973.2 | 1 | UniProt (P61925) In PDB | Homo sapiens | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
| 3 | A | 2-[(2-aminoethyl)amino]-N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-(pyridin-4-yl)benzamide | non-polymer | 390.5 | 1 | Chemie (J0G) | |||
| 4 | water | water | 18.0 | 454 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42810.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 390.5 | |
| All* | Total formula weight | 43201.3 |
