6E7D

Structure of the inhibitory NKR-P1B receptor bound to the host-encoded ligand, Clr-b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	C-type lectin domain family 2 member D	polymer	124	14763.4	16	UniProt (Q91V08) Pfam (PF00059) In PDB	Mus musculus (Mouse)	C-type lectin-related protein B,Clr-b,Lectin-like transmembrane protein,Osteoclast inhibitory lectin
2	Q, R, S, T, U...	Killer cell lectin-like receptor subfamily B member 1B allele B	polymer	137	15631.5	8	UniProt (Q99JB4) Pfam (PF00059) In PDB	Mus musculus (Mouse)	CD161 antigen-like family member B,Inhibitory receptor NKR-P1B,Lymphocyte antigen 55d,Ly-55d,NKR-P1D,Natural killer cell surface protein NKR-P1B allele B6
3	Q, R, S, T, U...	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4	R, S, T, U, V...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
5		water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 74 - 194 (UniProt: Q91V08)

PDB	External Database	Details
Met 73	-	initiating methionine
Ala 195	-	expression tag
Ser 196	-	expression tag

Q, R, S, T, U, V, W, X: 89 - 215 (UniProt: Q99JB4)

PDB	External Database	Details
Thr 87	-	expression tag
Gly 88	-	expression tag
Gly 118	Cys 118	engineered mutation
Gly 216	-	expression tag
Thr 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	361266.5
Non-Polymers*	Number of molecules	17
	Total formula weight	2634.2
All*	Total formula weight	363900.8

*Water molecules are not included.