6E78
Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 115 | 12610.1 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (Human) | ATTR,Prealbumin,TBPA |
| 2 | C, D (A, B) | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID | non-polymer | 250.2 | 2 | Chemie (1FL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 124 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ala 38 | Asp 58 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25220.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 500.4 | |
| All* | Total formula weight | 25720.6 |
