6E6E
DGY-06-116, a novel and selective covalent inhibitor of SRC kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Proto-oncogene tyrosine-protein kinase Src | polymer | 276 | 31656.4 | 8 | UniProt (P12931) Pfam (PF07714) | Homo sapiens (Human) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | N-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | non-polymer | 599.1 | 8 | Chemie (HVY) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 253250.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4793.0 | |
| All* | Total formula weight | 258043.8 |
