6E69
Ortho-substituted phenyl sulfonyl fluoride and fluorosulfate as potent elastase inhibitory fragments
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Neutrophil elastase | polymer | 218 | 23319.0 | 4 | UniProt (P08246) Pfam (PF00089) | Homo sapiens (Human) | Bone marrow serine protease, Elastase-2, Human leukocyte elastase, HLE, Medullasin, PMN elastase |
| 2 | E, G, I, J (E, G, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 4 | In PDB GlyTouCan (G21290RB) | |||
| 3 | F, H, K (F, H, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | L, M, O, P (A, B, C, D) | 2-(fluorosulfonyl)benzene-1-sulfonic acid | non-polymer | 240.2 | 4 | Chemie (HVP) | |||
| 5 | N (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93275.9 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3555.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1182.1 | |
| All* | Total formula weight | 98013.4 |
