6E5U
Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus NS1 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Nuclear RNA export factor 1 | polymer | 508 | 57482.4 | 4 | UniProt (Q9UBU9) Pfam (PF09162) Pfam (PF22602) Pfam (PF03943) | Homo sapiens (Human) | Tip-associated protein,Tip-associating protein,mRNA export factor TAP |
| 2 | B, D, F, H (B, D, F, H) | NTF2-related export protein 1 | polymer | 140 | 15859.8 | 4 | UniProt (Q9UKK6) Pfam (PF02136) | Homo sapiens (Human) | Protein p15 |
| 3 | I, J, K, P (K, L, M, J) | Non-structural protein 1 | polymer | 77 | 8449.5 | 4 | UniProt (I7CAR2) Pfam (PF00600) | Influenza A virus | NS1 |
| 4 | L, M, N, O (U, V, X, Y) | Non-structural protein 1 | polymer | 153 | 17160.7 | 4 | UniProt (I7CAR2) Pfam (PF00600) | Influenza A virus | NS1 |
Sequence modifications
A, C, E, G: 116 - 619 (UniProt: Q9UBU9)
K, L, M, J: 1 - 72 (UniProt: I7CAR2)
U, V, X, Y: 78 - 230 (UniProt: I7CAR2)
| PDB | External Database | Details |
|---|---|---|
| Gly 112 | - | expression tag |
| Ala 113 | - | expression tag |
| Met 114 | - | expression tag |
| Gly 115 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 38 | Arg 38 | engineered mutation |
| Ala 41 | Lys 41 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| - | Thr 80 | deletion |
| - | Met 81 | deletion |
| - | Ala 82 | deletion |
| - | Ser 83 | deletion |
| - | Ala 84 | deletion |
| Pro 85 | Leu 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 395809.8 | |
| All* | Total formula weight | 395809.8 |
