6E4Q

Crystal Structure of the Drosophila Melanogaster Polypeptide N-Acetylgalactosaminyl Transferase PGANT9A in Complex with UDP and Mn2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	polypeptide N-acetylgalactosaminyltransferase 9	polymer	510	58274.7	4	UniProt (Q8MRC9) Pfam (PF00535) Pfam (PF00652)	Drosophila melanogaster (Fruit fly)	pp-GaNTase 9,Protein-UDP acetylgalactosaminyltransferase 9,UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9
2	E, J, O, T (A, B, C, D)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN) PubChem (27854)
3	F, K, P, U (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
4	G, L, Q, V (A, B, C, D)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241)
5	H, I, M, R, S... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
6	N, X (B, D)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL) PubChem (753)
7	AA, BA, Y, Z (C, D, A, B)	water	water		18.0	194	Chemie (HOH)

Sequence modifications

A, B, C, D: 146 - 650 (UniProt: Q8MRC9)

PDB	External Database	Details
Gly 141	-	expression tag
Gly 142	-	expression tag
Gly 143	-	expression tag
Gly 144	-	expression tag
Gly 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	233098.8
Non-Polymers*	Number of molecules	20
	Total formula weight	3277.8
All*	Total formula weight	236376.6

*Water molecules are not included.