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6E3V

Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable TTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164844.11Homo sapiens
3C
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')polymer103085.01Homo sapiens
4D
(D)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01Homo sapiens
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidinenon-polymer481.21Chemie (1FZ)
8J, K, L, M
(A, T, P, D)
waterwater18.0196Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47706.9
Non-Polymers*Number of molecules5
Total formula weight575.8
All*Total formula weight48282.7
*Water molecules are not included.

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PDB entries from 2024-11-13

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