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6E1Z

Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
WD repeat-containing protein 5polymer31334391.02UniProt (P61964)
Pfam (PF25175)
Homo sapiens (Human)BMP2-induced 3-kb gene protein
2C, D
(A, B)
5-[(1H-imidazol-1-yl)methyl]furan-2-carboxylic acidnon-polymer192.22Chemie (HLP)
3E, F
(A, B)
waterwater18.0993Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68782.0
Non-Polymers*Number of molecules2
Total formula weight384.3
All*Total formula weight69166.3
*Water molecules are not included.

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PDB entries from 2026-01-28

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